Amyris Enhances Strategic Partnership With Total for Renewable Diesel and Jet Fuels

31 July 2012 – Amyris, Inc. (Nasdaq:AMRS) signed today an amendment to its existing technology collaboration agreement with Total (Paris:TOTF). Under the enhanced collaboration, Total reaffirms its commitment to Amyris’s technology and dedicates its $82 million funding budget over the next three years exclusively for the deployment of Biofene, Amyris’s renewable farnesene, for production of renewable diesel and jet fuel. Upon completion of the research and development program, Total and Amyris intend to form a joint venture company that would have exclusive rights to produce and market renewable diesel and/or jet fuel, as well as non-exclusive rights to other specialty products.

“Today we reaffirm our strategic relationship with Total to achieve our joint development and commercialization objectives for renewable diesel and jet fuel,” said John Melo, President & CEO of Amyris. “We are appreciative of Total’s ongoing support of Amyris.In addition to Amyris’ continued development of jet and diesel businesses in Brazil independently, this enhanced collaboration provides a global platform for the future growth in fuels under a future joint venture with Total,” Melo concluded.

“Amyris’ best-in-class technology to produce renewable hydrocarbons has proven performance attributes,” said Philippe Boisseau, President, Supply-Marketing and member of Total’s Executive Committee. “With this refocused partnership, we’ll reach our business objectives, expand our ability to become a key supplier in renewable fuels and better meet our customers’ highest demands,” Boisseau concluded.

Under today’s announcement, Total agreed to fund $30 million during the third quarter of 2012. Additional funding will be triggered by Total at annual decision points in mid 2013 and 2014. Detailed information is included in Amyris’s SEC filing associated with this transaction.

“Amyris and Total have had a successful research partnership since 2010 and we continue, through this amended collaboration, to pursue our shared strategy of building the world’s leading renewable technology platform,” said Arthur D. Levinson, Ph.D., Chairman of the Board of Directors of Amyris. “Today’s agreement deepens this long-term partnership and enables Amyris to continue investing in its core technology while accessing the market know-how and scale-up capability of Total,” concluded Levinson.

About the Technology

Amyris has developed advanced microbial engineering and screening technologies that modify the way microorganisms process sugars. Amyris is using this industrial synthetic biology platform to design microbes, primarily yeast, and use them as living factories in established fermentation processes to convert plant-sourced sugars into renewable chemical and transportation fuel products.

Amyris operates laboratories and a pilot plant in California as well as a pilot plant and demonstration facility in Brazil. Amyris has been scaling its Biofene production through various production arrangements and expects to operate its first dedicated commercial scale facility in Brazil by early 2013.

This technology will help make it possible for producers to blend renewable hydrocarbons produced from sustainable biomass and organic waste into fuel in proportions that significantly exceed the current 7% set by European Union regulations or other government policies. Renewable fuels developed by Total and Amyris will deliver energy density, engine performance, and storage properties comparable to the best petroleum fuels.

About Amyris

Amyris is an integrated renewable products company focused on providing sustainable alternatives to a broad range of petroleum-sourced products. Amyris uses its industrial synthetic biology platform to convert plant sugars into a variety of hydrocarbon molecules – flexible building blocks that can be used in a wide range of products. Amyris is commercializing these products both as No Compromise® renewable ingredients in cosmetics, flavors and fragrances, polymers, lubricants and consumer products, and also as No Compromise renewable diesel and jet fuel. Amyris Brasil Ltda., a subsidiary of Amyris, oversees the establishment and expansion of Amyris’s production in Brazil. For more information, visit www.amyris.com.

The Amyris, Inc. logo is available at http://www.globenewswire.com/newsroom/prs/?pkgid=12462

Amyris Forward-Looking Statements

This release contains forward-looking statements, and any statements other than statements of historical facts could be deemed to be forward-looking statements. These forward-looking statements include, among other things, statements regarding future events (such as the timing and receipt of funds under the collaboration agreements, research and development, production and commercialization of potential products, timing for establishment and operation of a production plant, formation of a joint venture to commercialize potential products, customer demand for potential products, and the anticipated benefits of the proposed collaboration) that involve risks and uncertainties. These statements are based on management’s current expectations and actual results and future events may differ materially due to risks and uncertainties, including those associated with any delays or failures in development, production or commercialization of products, liquidity and ability to fund capital expenditures, Amyris’s reliance on third parties to achieve its goals, and other risks detailed in the “Risk Factors” section of Amyris’s Form 10-Q, as filed on May 9, 2012. Amyris disclaims any obligation to update information contained in these forward-looking statements whether as a result of new information, future events, or otherwise.

Amyris, No Compromise and Biofene are trademarks or registered trademarks of Amyris, Inc.

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